HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59398561, compound → HCID 59398567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59398561 | HCID 59398561 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59398567 | HCID 59398567 | 29.6% |
Reaction Steps
[4-(2-Fluoroethyl)-3-(trifluoromethyl)phenyl]carbamic acid benzyl ester (194 mg, 0.8 mmol) was dissolved in methanol (4 mL), and palladium carbon (10%, 45 mg) was added thereto. The resulting mixture was stirred under hydrogen atmosphere at room temperature for 3 hours. The catalyst was removed by filtration to give 4-(2-fluoroethyl)-3-(trifluoromethyl)aniline (49 mg, 29%) as a light-yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299252B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-5ff1d50f191b4cb5bf744cfe6694612f |
| Source note | uspto-grants-2012_10 |