HCID 72288086, compound → HCID 59398529, compound

Participants

Reaction Steps

[3-(Trifluoromethyl)-4-(3,3,3-trifluoropropenyl)phenyl]carbamic acid benzyl ester (103 mg, 0.27 mmol) was dissolved in methanol (10 mL), and palladium carbon (10%, 11 mg) was added thereto. The resulting mixture was stirred under hydrogen atmosphere at room temperature for 3 hours. The catalyst was removed by filtration, and the filtrate was concentrated under reduced pressure to give 3-(trifluoromethyl)-4-(3,3,3-trifluoropropyl)aniline (56.6 mg, 83%) as a light-yellow oil.

Provenance & Evidence