HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67421830, compound → HCID 46214207, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67421830 | HCID 67421830 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 46214207 | HCID 46214207 | 90.5% |
Reaction Steps
In a 25 ml round-bottomed flask, 0.25 g of 4-(2,4-bis(benzyloxy)phenyl)piperidine-1-carboxylic acid butylamide is dissolved in 9 ml of methanol in the presence of 0.1 g of palladium-on-charcoal at 10%. The reaction mixture is stirred for 4 hours under a hydrogen atmosphere. The reaction mixture is filtered. 0.14 g of 4-(2,4-dihydroxyphenyl)piperidine-1-carboxylic acid butylamide is obtained. Yield=90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08299259B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-6086bcb8c3ad4e5289962b95c50918fb |
| Source note | uspto-grants-2012_10 |