1-Iodopropane → HCID 59620392, compound

HRID 2070136Notes

Reaction equation

HRID 2070136 reaction equation
[C:1]([O:5][C:6]([NH:8][C@@H:9]([C:20]([OH:22])=[O:21])[CH2:10][C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[NH:13][CH:12]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].I[CH2:24][CH2:25][CH3:26]>>[C:1]([O:5][C:6]([NH:8][C@H:9]([CH2:10][C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[N:13]([CH2:24][CH2:25][CH3:26])[CH:12]=1)[C:20]([OH:22])=[O:21])=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 336431-IodopropaneHCID 111050N-((tert-Butoxy)carbonyl)-D-tryptophan

Product 1

HCID 59620392HCID 59620392, compoundYield 97.5%

Procedure

The procedure of Referential Example 1(a) was repeated, except that N-tert-butoxycarbonyl-D-tryptophan (1.0 g) and 1-iodopropane (838 mg) were used, whereby the title compound (1.11 g) was yielded.

Sources & evidence

ORD record
ord-1ac457a5d5b74ccb947474d4d9ff3f93
Source dataset
uspto-grants-2012_10
Patent number
US08299255B2

Reaction notes

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