反应详情

温度

110 °C

N-(8-Amino-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)acetamide (8.4 g) was added to concentrated hydrochloric acid (84 mL), and the mixture was heated at 110° C. for three hours while being stirred, followed by stirring under cooling on ice. The formed precipitates were recovered through filtration, and the thus-obtained solid was washed with ethanol, followed by drying, whereby the title compound (9.17 g) was yielded.

1. stirringby stirring
2. temperatureunder cooling on ice
3. customThe formed precipitates
4. filtrationwere recovered through filtration
5. washthe thus-obtained solid was washed with ethanol
6. customby drying