Calcium Acetate → HCID 86628952, compound

HRID 2070224Notes

Reaction equation

HRID 2070224 reaction equation
[CH3:1][S:2][C:3]([S:11][CH3:12])([CH2:7][CH2:8][S:9][CH3:10])[C:4]([OH:6])=[O:5].C([O-])(=O)C.[Ca+2:17].C([O-])(=O)C>O.CC(C)=O>[CH3:12][S:11][C:3]([S:2][CH3:1])([CH2:7][CH2:8][S:9][CH3:10])[C:4]([O-:6])=[O:5].[Ca+2:17].[CH3:12][S:11][C:3]([S:2][CH3:1])([CH2:7][CH2:8][S:9][CH3:10])[C:4]([O-:6])=[O:5]

Participants

5

Reactant 2

HCID 6116Calcium AcetateHCID 44473618HCID 44473618, compound

Product 1

HCID 86628952HCID 86628952, compoundYield 98.4%

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent2×

Procedure

16.6 g of 2,2,4-tris(methylthio)butanoic acid (4) (73.3 mmol) were dissolved in a mixture of 140 ml of H2O and 35 ml of acetone. Subsequently, a solution of 6.2 g of calcium acetate (93%) and 22 ml of H2O was slowly added dropwise at 20° C. with vigorous stirring. After a short time a white solid precipitated out which was filtered off after 30 minutes. The resulting white solid was washed twice with 200 ml of H2O each time, then with 200 ml of acetone and 200 ml of diethyl ether, and dried in a drying cabinet. A total of 17.7 g of calcium 2,2,4-tris(methylthio)butanoate (5) (M=490.8 g/mol, yield=98%) were isolated.

Workup

  1. customAfter a short time a white solid precipitated out which
  2. filtrationwas filtered off after 30 minutes
  3. washThe resulting white solid was washed twice with 200 ml of H2O each time
  4. dry with materialwith 200 ml of acetone and 200 ml of diethyl ether, and dried in a drying cabinet

Sources & evidence

ORD record
ord-dfde202eaa8a4b2dbe1c4131ec2c39c3
Source dataset
uspto-grants-2012_10
Patent number
US08299293B2

Reaction notes

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