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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2070342Generated: October 25, 2026

(2-Methyl-5-nitrophenyl)pyrrolidine → 4-Methyl-3-(pyrrolidin-1-yl)aniline

https://huagongshe.com/reaction/2070342

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Methyl-5-nitrophenyl)pyrrolidineHCID 69558510—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product4-Methyl-3-(pyrrolidin-1-yl)anilineHCID 17604049—

Reaction Steps

The mixture containing (2-methyl-5-nitrophenyl)pyrrolidine in methanol with catalytic amount of 10% Pd/C was hydrogenated to yield 4-methyl-3-pyrrolidinylphenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08299108B2
Source datasetuspto-grants-2012_10
ORD IDord-a5e800b91c0644ab91b8f80f4d3cf579
Source noteuspto-grants-2012_10