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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2070347Generated: October 31, 2026

4-[4-(Methylamino)-3-nitrophenoxy]pyridine-2-carboxamide → 4-(3-Amino-4-(methylamino)phenoxy]pyridine-2-carboxamide

https://huagongshe.com/reaction/2070347

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[4-(Methylamino)-3-nitrophenoxy]pyridine-2-carboxamideHCID 59789982—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product4-(3-Amino-4-(methylamino)phenoxy]pyridine-2-carboxamideHCID 22040355—

Reaction Steps

The mixture containing 4-[4-(methylamino)-3-nitrophenoxy]pyridine-2-carboxamide in methanol with catalytic amount of 10% Pd/C was hydrogenated to yield 4-(3-amino-4-(methylamino)phenoxy]pyridine-2-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08299108B2
Source datasetuspto-grants-2012_10
ORD IDord-d8a1b9ccf1304174a5770f772489c449
Source noteuspto-grants-2012_10