反应详情

The title compound can be prepared from potassium acetate and 8-(3-bromopropoxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one (Example 30) following the procedures outlined in Examples 52 & 42. 1H NMR (400 MHz, DMSO-d6): δ 9.52 (s, 1H), 8.81 (s, 2H), 7.94 (d, 1H), 7.20 (d, 1H), 4.64 (s, 1H), 4.44 (t, 1H), 4.07 (t, 2H), 3.92 (s, 3H), 3.57 (q, 2H), 1.82 (m, 2H); MS (ESI): 410.8.