Methanol → HCID 21413341, compound

Participants

Reaction Steps

To a solution of 8-chloro-4-hydroxy-6-phenyl-4H-s-triazolo[1,5-a][1,4]benzodiazepine-2-carboxamide (3/2 hydrate) in methanol is added a small amount of concentrated sulfuric acid, and the mixture is treated in the same manner as that of Example 3 to give 8-chloro-4-methoxy-6-phenyl-4H-s-triazolo[1,5-a][1,4]benzodiazepine-2-carboxamide as crystals (1/3 hydrate). This product is identical with the product in Example 3 with respect to melting point and infrared absorption spectrum.

Provenance & Evidence