HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21413155, compound → 2-Chloro-3-(4-chlorophenyl)pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21413155 | HCID 21413155 | — |
| Reactant | alpha-Methyl-3-(p-chlorophenyl)pyrazineacetamide | HCID 21413205 | — |
| Reactant | Diethyl alpha-methyl-3-(p-chlorophenyl)pyrazinylmalonate | HCID 21413210 | — |
| Reactant | Ethyl alpha-methyl-3-(p-chlorophenyl)pyrazineacetate | HCID 21413211 | — |
| Reactant | HCID 178517835 | HCID 178517835 | — |
| Product | 2-Chloro-3-(4-chlorophenyl)pyrazine | HCID 13199889 | — |
Reaction Steps
2-Chloro-3-(p-chlorophenyl)pyrazine is prepared by the method of Karmas and Spoerri. (loc. cit.), using 3-(p-chlorophenyl)pyrazinol as the starting material. Starting with this material and using the procedures of Examples V, VI, IX, and XI, the products obtained are diethyl α-methyl-3-(p-chlorophenyl)pyrazinylmalonate, ethyl α-methyl-3-(p-chlorophenyl)pyrazineacetate, α-methyl-3-(p-chlorophenyl)pyrazineacetic acid, and α-methyl-3-(p-chlorophenyl)pyrazineacetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04046763 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-d0a69c353d944da595f2df62b3ae3b17 |
| Source note | uspto-grants-1977_09 |