Trimethyl phosphite → HCID 53801769, compound

Participants

Reaction Steps

1-Chloro-3-(5-chloropyrid-2-yloxy)-2-semicarbazonopropane (322 mg.) and trimethyl phosphite (720 mg.) were mixed and heated at 70°-100° C., with stirring, for 11/2 hours. The mixture was evaporated to dryness, finally under high vacuum, to give dimethyl 3-(5-chloropyrid-2-yloxy)-2-semicarbazonopropylphosphonate, RF = 0.15 (5% v/v methanol in ethyl acetate), the required starting material.

Provenance & Evidence