Isothiocyanatotrimethylsilane → HCID 21413759, compound

HRID 2071412Notes

Reaction equation

[CH3:1][C:2]1[N:3]=[C:4]2[C:9](=[C:10]3[C:15]=1[CH2:14][CH2:13][CH2:12][CH2:11]3)[CH2:8][CH2:7][CH2:6][CH2:5]2.C([Li])CCC.C[Si]([N:25]=[C:26]=[S:27])(C)C>>[CH3:1][C:2]1[N:3]=[C:4]2[C:9](=[C:10]3[C:15]=1[CH2:14][CH2:13][CH2:12][CH2:11]3)[CH2:8][CH2:7][CH2:6][CH:5]2[C:26](=[S:27])[NH2:25]

Participants

Reactant 3

HCID 75297Isothiocyanatotrimethylsilane

HCID 11298606Phenanthridine, 1,2,3,4,7,8,9,10-octahydro-6-methyl-

HCID 178418339Butyllithium

Product 1

HCID 21413759HCID 21413759, compound

Procedure

By the method of Example 2, 1,2,3,4,7,8,9,10-octahydro-6-methyl-phenanthridine is reacted with n-butyl-lithium solution and the resulting anion is reacted with trimethylsilyl isothiocyanate to give 1,2,3,4,7,8,9,10-octahydro-6-methylphenanthridine-4-thiocarboxamide.

Sources & evidence

ORD record: ord-66812808f29d49579c398d7b84bfc254
Source dataset: uspto-grants-1977_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04046895

Reaction notes

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