HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-(Piperidin-3-yl)benzene-1,2-diol--hydrogen bromide (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3-(3,4-Dimethoxyphenyl)piperidine hydrochloride | HCID 21413780 | — |
| Product | 4-(Piperidin-3-yl)benzene-1,2-diol--hydrogen bromide (1/1) | HCID 3046209 | — |
Reaction Steps
A solution of 5 g of the hydrochloride of Step C in 25 ml of 66% hydrobromic acid was heated at 115° C. for an hour and excess hydrobromic acid was removed under reduced pressure. The residue was empasted with ethyl acetate and was crystallized from ethanol to obtain 3.85 g of 3-(3',4'-dihydroxyphenyl)-piperidine hydrobromide melting at 224° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04046901 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-eba4f089f731430fa43b8ae31ba8113a |
| Source note | uspto-grants-1977_09 |