HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 178482312, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 2-Chloro-3,3-dimethyl-4-phenyl-3,4-dihydro-4-quinolinol | HCID 21411733 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 178482312 | HCID 178482312 | — |
Reaction Steps
2-Chloro-3,4-dihydro-3,3-dimethyl-4-phenylquinolin-4-ol (1.43g., 0.005 mole) was dissolved in a mixture of a 33% w/v solution of methylamine in ethanol (40 ml.) and pyridine (0.79g.). The solution was stirred for four hours, after which the methylamine and ethanol were evaporated off to leave a residue, which was recrystallised twice from isopropyl alcohol to give the title compound (0.96g., m.p. 192° - 194° C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04048177 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-fe42325fe5804467a0252f344b831b76 |
| Source note | uspto-grants-1977_09 |