HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 21411740, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 2-Chloro-3,3-dimethyl-4-phenyl-3,4-dihydro-4-quinolinol | HCID 21411733 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 21411740 | HCID 21411740 | 68.7% |
Reaction Steps
2-Chloro-3,4-dihydro-3,3-dimethyl-4-phenylquinolin-4-ol (0.7g., 0.0025 mole) was dissolved in dry dioxan (10 ml.). Triethylamine (0.5g) followed by N-methylpiperazine (1.92g.) were added and the mixture stirred for 4 hours. The mixture was then evaporated down to a white solid residue which was recrystallised from isopropyl alcohol to give the title compound (0.60g., m.p. 268° - 269° C) [Found: C, 75.6; H, 8.1; N, 12.15% C22H27N3O requires C, 75.6; H, 7.8; N, 12.0%].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04048177 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-11465f434f934c74b12d263159944c0a |
| Source note | uspto-grants-1977_09 |