HCID 21411861, compound → Perchloric acid--4-chloro-2-[(pyrrolidin-1-yl)methyl]-1H-pyrrole (1/1)

HRID 2071678Notes

Reaction equation

HRID 2071678 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[Cl:6][C:7]1[CH:8]=[C:9]([CH:12]=[N+:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[NH:10][CH:11]=1>C(OCC)(=O)C.[Pt]=O>[Cl:1]([OH:5])(=[O:4])(=[O:3])=[O:2].[Cl:6][C:7]1[CH:8]=[C:9]([CH2:12][N:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[NH:10][CH:11]=1

Participants

4

Reactant 1

HCID 21411861HCID 21411861, compound

Product 1

HCID 21411886Perchloric acid--4-chloro-2-[(pyrrolidin-1-yl)methyl]-1H-pyrrole (1/1)

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 8857Ethyl AcetateSolvent

Procedure

A suspension of 114.4 g. (0.404 mole) of the product of Example V in 1 l of ethyl acetate is shaken with 1.2 g of platinum oxide under an initial hydrogen pressure of 48 psi. After being shaken for 72 hours, the reaction mixture is filtered and the filter cake is washed exhaustively with ethyl acetate. The filtrate is evaporated to give 4-chloro- 2-(1-pyrrolidinomethyl)pyrrole perchlorate as a brown oil.

Workup

  1. additionA suspension of 114.4 g
  2. filtrationthe reaction mixture is filtered
  3. washthe filter cake is washed exhaustively with ethyl acetate
  4. customThe filtrate is evaporated

Sources & evidence

ORD record
ord-30c3851b103542b199d0b3aba89a32e9
Source dataset
uspto-grants-1977_09
Patent number
US04048191

Reaction notes

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