Methylamine → HCID 178485016, compound

HRID 2071928Notes

Reaction equation

HRID 2071928 reaction equation
[CH3:1][NH2:2].[C:3]([NH:5][C:6](=[N:9][CH2:10][CH2:11][S:12][CH2:13][C:14]1[S:18][CH:17]=[N:16][C:15]=1[CH3:19])SC)#[N:4]>C(O)C>[C:3]([NH:5][C:6]([NH:2][CH3:1])=[N:9][CH2:10][CH2:11][S:12][CH2:13][C:14]1[S:18][CH:17]=[N:16][C:15]=1[CH3:19])#[N:4]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 21410020HCID 21410020, compound

Product 1

HCID 178485016HCID 178485016, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of 75 ml. of 33% methylamine in ethanol is added to a solution of the N-cyano-N'-[2-(4-methyl-5-thiazolylmethylthio)ethyl]-S-methylisothiourea prepared above in 30 ml. of ethanol. The reaction mixture is set aside at ambient temperature for 2.5 hours, and the precipitate is collected to give N-cyano-N'-methyl-N"-[2-(4-methyl-5-thiazolylmethylthio)ethyl]guanidine.

Workup

  1. customprepared above in 30 ml
  2. customthe precipitate is collected

Sources & evidence

ORD record
ord-edf36bd054094372992741308939d72c
Source dataset
uspto-grants-1977_09
Patent number
US04049669

Reaction notes

Loading…