Benzoyl chloride, 3,4-dichloro- → HCID 21409861, compound

HRID 2071993Notes

Reaction equation

HRID 2071993 reaction equation
[CH3:1][NH:2][CH2:3][C:4]1([N:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1.[Cl:16][C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][C:25]=1[Cl:26])[C:20](Cl)=[O:21]>C1C=CC=CC=1>[ClH:16].[CH3:1][N:2]([CH2:3][C:4]1([N:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1)[C:20](=[O:21])[C:19]1[CH:23]=[CH:24][C:25]([Cl:26])=[C:17]([Cl:16])[CH:18]=1

Participants

4

Reactant 2

HCID 76403Benzoyl chloride, 3,4-dichloro-HCID 21409890N-Methyl-1-[1-(piperidin-1-yl)cyclohexyl]methanamine

Product 1

HCID 21409861HCID 21409861, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

Solutions of 1-[1-[(methylamino)methyl]cyclohexyl] piperidine (1.1 g., 0.005 mole) in dry benzene (25 ml) and 3,4-dichlorobenzoyl-chloride (1.0 g., 0.005 mole) in dry benzene (50 ml) were mixed and heated under reflux (steam bath) for 1 hr. The precipitate was filtered washed with benzene and dried. (1. 6 g.) m.p. 222° (dec.)

Workup

  1. temperatureheated
  2. temperatureunder reflux (steam bath) for 1 hr
  3. filtrationThe precipitate was filtered
  4. washwashed with benzene
  5. customdried

Sources & evidence

ORD record
ord-e0f7b7a397ee4f8db7658706442f6d2c
Source dataset
uspto-grants-1977_09
Patent number
US04049663

Reaction notes

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