反应详情

To 3.0 g (0.079 mol) of 2-chloro-3-((4-(2,2-dichloro-1,1-difluoroethoxy)phenyl)sulfonyl)propanenitrile in 100 ml of benzene was added a slight molar excess of triethylamine. The reaction mixture was filtered to remove the triethylamine hydrochloride produced. The benzene was removed in vacuo from the filtrate, and the residue which remained was crystallized from methanol/ water to give 1.5 g of the title compound as a tan solid, mp 89°-90° C.

1. filtrationThe reaction mixture was filtered
2. customto remove the triethylamine hydrochloride
3. customproduced
4. customThe benzene was removed in vacuo from the filtrate
5. customthe residue which remained was crystallized from methanol/ water