Acetic Anhydride → N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

HRID 2072147Notes

Reaction equation

HRID 2072147 reaction equation
[CH:1]1([NH2:11])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[C:12](OC(=O)C)(=[O:14])[CH3:13]>>[CH:1]1([NH:11][C:12](=[O:14])[CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 180661,2,3,4-Tetrahydro-1-naphthylamine

Product 1

HCID 11063199N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

Procedure

1,2,3,4-Tetrahydro-1-naphthylamine is stirred with acetic anhydride to afford N-(1,2,3,4-tetrahydro-1-naphthyl)acetamide, which is oxidized to N-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)acetamide by the method of Example 1.

Sources & evidence

ORD record
ord-edacb993463f42bf81d484de32af9d4e
Source dataset
uspto-grants-1977_09
Patent number
US04049717

Reaction notes

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