反应详情

In the manner described in Example 5, (+)-1,2,3,4- tetrahydro-4-oxo-1-naphthylamine, which is obtaind by acid hydrolysis (refluxing in HC1)of (-)-N-(1,2,3,4-tetrahydro-4- oxo-1-naphthyl)formamide followed by neutralization, is allowed to react with benzoyl isocyanate. The resulting 1-benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)urea is then hydrolyzed with alkali as in Example 6 to afford (-)-1,2,3,4-tetrahydro-4-oxo-1-naphthylurea.

1. customis obtaind by acid hydrolysis (