HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl isocyanate → Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl isocyanate | HCID 78210 | — |
| Reactant | 4-amino-3,4-dihydro-2H-naphthalen-1-one | HCID 13738660 | — |
| Reactant | 1-Benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)urea | HCID 20537302 | — |
| Reactant | N-(4-Oxo-1,2,3,4-tetrahydronaphthalen-1-yl)formamide | HCID 20537306 | — |
| Product | Urea, (1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl)- | HCID 3628438 | — |
Reaction Steps
In the manner described in Example 5, (+)-1,2,3,4- tetrahydro-4-oxo-1-naphthylamine, which is obtaind by acid hydrolysis (refluxing in HC1)of (-)-N-(1,2,3,4-tetrahydro-4- oxo-1-naphthyl)formamide followed by neutralization, is allowed to react with benzoyl isocyanate. The resulting 1-benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)urea is then hydrolyzed with alkali as in Example 6 to afford (-)-1,2,3,4-tetrahydro-4-oxo-1-naphthylurea.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051183 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-7e6ceabec91e43dd8f9267c54e6c0d73 |
| Source note | uspto-grants-1977_09 |