Hydrochloric Acid → HCID 53840723, compound

HRID 2072398Notes

Reaction equation

HRID 2072398 reaction equation
Cl.[NH2:2][CH:3]([CH2:7][C:8]1[CH:9]=[CH:10][C:11]2[O:15][C:14](=[O:16])[NH:13][C:12]=2[CH:17]=1)[C:4]([OH:6])=[O:5].Cl.[CH3:19]O>>[CH3:19][O:5][C:4](=[O:6])[CH:3]([NH2:2])[CH2:7][C:8]1[CH:9]=[CH:10][C:11]2[O:15][C:14](=[O:16])[NH:13][C:12]=2[CH:17]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 70618768HCID 70618768, compound

Product 1

HCID 53840723HCID 53840723, compound

Procedure

The product from Example 17 is held for 6 hours at reflux in 1500 ml of methanol saturated with HCl gas. The alcoholic solution is evaporated to yield a product which is recrystallized from water or methanol: ether to yield the Example 21 title compound.

Workup

  1. customThe alcoholic solution is evaporated
  2. customto yield a product which
  3. customis recrystallized from water or methanol

Sources & evidence

ORD record
ord-6fccc103d29e4ebca2b9fdfb22f577a7
Source dataset
uspto-grants-1977_09
Patent number
US04051251

Reaction notes

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