3-Amino-4,7-dichloroindazole-2-carboxylic acid ethyl ester → 3-Amino-4,7-dichloroindazole

HRID 2072407Notes

Reaction equation

HRID 2072407 reaction equation
C(OC([N:6]1[C:14]([NH2:15])=[C:13]2[C:8]([C:9]([Cl:17])=[CH:10][CH:11]=[C:12]2[Cl:16])=[N:7]1)=O)C>C(OC(OC(OCC)=O)=O)C>[NH2:15][C:14]1[C:13]2[C:8](=[C:9]([Cl:17])[CH:10]=[CH:11][C:12]=2[Cl:16])[NH:7][N:6]=1

Participants

3

Reactant 1

HCID 541624823-Amino-4,7-dichloroindazole-2-carboxylic acid ethyl ester

Product 1

HCID 214092343-Amino-4,7-dichloroindazole

Reagents, catalysts & solvents 1

HCID 3051Diethyl PyrocarbonateSolvent

Procedure

Analogously to Example 1, 0.15 mol of 3-amino-4,7-dichloroindazole in 100 ml of pyrocarbonic acid diethyl ester gives 3-amino-4,7-dichloroindazole-2-carboxylic acid ethyl ester (melting point: 143°-145° C; 69% of theory) in 5 hours at 50° C.

Sources & evidence

ORD record
ord-d7da52d7cb0e4911871ed5166e35468b
Source dataset
uspto-grants-1977_09
Patent number
US04051252

Reaction notes

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