HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-5-trifluoromethylindazole-1-carboxylic acid ethylamide → Ethyl isocyanate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-5-trifluoromethylindazole-1-carboxylic acid ethylamide | HCID 53966537 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Ethyl isocyanate | HCID 8022 | — |
| Product | Bay-H-1127 | HCID 16736 | — |
Reaction Steps
Analogously to Example 46, 0.05 mol of 3-amino-5-trifluoromethylindazole and 0.05 mol of ethyl isocyanate in 100 ml of pyridine give 3-amino-5-trifluoromethylindazole-1-carboxylic acid ethylamide (melting point: 131°-132° C; 47% of theory) in 1 hour at 10°-15° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051252 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-3c4284e2fa024bf89839ce2124d42c2c |
| Source note | uspto-grants-1977_09 |