HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Isocyanate → HCID 21409338, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | 3-Methyl-4-nitrophenol | HCID 17412 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 21409338 | HCID 21409338 | — |
Reaction Steps
3-Methyl-4-nitrophenol (46.0g., 0.30 mole) was dissolved in tetrahydrofuran (200 ml.) and triethylamine (2 ml.). To this solution was added dropwise methylisocyanate (18.8g., 0.33 mole, 25 ml.) which resulted in an exotherm to about 40° C. Refluxing for one hour, followed by quenching in excess water, yieldig a light tan precipitate. After filtration and drying the material (51g.) melted at .99°-101° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051254 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-a92841fabf55417f9667d201ac6ee693 |
| Source note | uspto-grants-1977_09 |