HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Phenyl-8-[(cis-1,2,3,4-tetrahydro-1-hydroxy-2-naphthalenyl)methyl]-1,3,8-triazaspiro[4.5]decan-4-one, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 54521082 | HCID 54521082 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Phenyl-8-[(cis-1,2,3,4-tetrahydro-1-hydroxy-2-naphthalenyl)methyl]-1,3,8-triazaspiro[4.5]decan-4-one, hydrochloride | HCID 131710902 | — |
Reaction Steps
1-Phenyl-8-[(cis-1,2,3,4-tetrahydro-1-hydroxy-2-naphthalenyl)methyl]-1,3,8-triazaspiro[4.5]decan-4-one (4.0 g) is slurried in ether and treated with excess ethereal hydrogen chloride. The resulting mixture is cooled for 16 hours and the resulting precipitate is collected to yield 3.9 g of the title compound, melting point 254°-255° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051248 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-cbea349b108a41eeafdaa3ddfd9ddb53 |
| Source note | uspto-grants-1977_09 |