反应详情

1-Phenyl-8-[(cis-1,2,3,4-tetrahydro-1-hydroxy-2-naphthalenyl)methyl]-1,3,8-triazaspiro[4.5]decan-4-one (4.0 g) is slurried in ether and treated with excess ethereal hydrogen chloride. The resulting mixture is cooled for 16 hours and the resulting precipitate is collected to yield 3.9 g of the title compound, melting point 254°-255° C.

1. temperatureThe resulting mixture is cooled for 16 hours
2. customthe resulting precipitate is collected