Hydrochloric Acid → HCID 131710904, compound

Participants

Reaction Steps

1-Phenyl-8-[(trans-1,2,3,4-tetrahydro-1-hydroxy-6-methoxy-2-naphthalenyl)methyl]-1,3,8-triazaspiro[4.5]-decan-4-one (2.5 g) is suspended in 100 ml of anhydrous ether and treated with one equivalent of ethereal hydrogen chloride. The resulting mixture is stirred at room temperature for one hour and then cooled. The precipitate is collected and washed with additional ether to yield 2.4 g of the title compound, melting point 258°-260° C.

Provenance & Evidence