HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-[(1,2,3,4-Tetrahydro-1-oxo-2-naphthalenyl)-methyl]-4-anilino isonipecotonitrile, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-[(1,2,3,4-Tetrahydro-1-oxo-2-naphthalenyl)-methyl]-4-anilino isonipecotonitrile | HCID 53821125 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-[(1,2,3,4-Tetrahydro-1-oxo-2-naphthalenyl)-methyl]-4-anilino isonipecotonitrile, hydrochloride | HCID 131710908 | — |
Reaction Steps
Finely-ground 1-[(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)-methyl]-4-anilino isonipecotonitrile (5.0 g) is slurried in absolute ethanol and treated with 1.2 equivalents of ethereal hydrogen chloride. The resulting mixture is cooled and filtered to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04051248 |
| Source dataset | uspto-grants-1977_09 |
| ORD ID | ord-48a7c1a3158041ad889a3637bd84b500 |
| Source note | uspto-grants-1977_09 |