Hydrochloric Acid → HCID 131710918, compound

Participants

Reaction Steps

1-Phenyl-8-[(1,2,3,4-tetrahydro-6,7-dimethyl-1-oxo-2-naphthalenyl)methyl]-1,3,8-triazaspiro[4.5]decan-4-one (15.0 g) is slurried in 150 ml of absolute ethanol and treated with 1.2 equivalents of ethereal hydrogen chloride. The resulting mixture is stirred at room temperature for 1 hour and then filtered to yield 14.7 g of the title compound, melting point 260°-262° C.

Provenance & Evidence