関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Sodium sulfide nonahydrate | HCID 73972 | — |
| 反応物 | 2-CHLORO-4-THIOCYANATOANILINE | HCID 591125 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-Amino-3-chlorobenzenethiol | HCID 19858566 | — |
反応手順
A solution of 2-chloro-4-thiocyanoaniline (36.9 g., 0.20 mole) in ethanol (100-200 ml.) is added to a stirred solution of sodium sulfide nonahydrate (48.04 g., 0.20 mole) in water (100 ml.) and the mixture warmed (50° C.) for 90 minutes. The cool reaction mixture is poured into water (1 liter) and dilute hydrochloric acid added to bring the pH up to 6.0-6.5. The product is extracted with ether, the ether washed with water and then dried. Removal of the drying agent and ether leaves 2-chloro-4-mercaptoaniline as a yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04913728 |
|---|
| 出典データセット | uspto-grants-1990_04 |
|---|
| ORD ID | ord-8b2d0530f3464ae095be8cceb561d521 |
|---|
| 出典メモ | uspto-grants-1990_04 |
|---|
