Hydrochloric Acid → 4-Amino-3-chlorobenzenethiol

HRID 2072592Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2072592
[Cl:1][C:2]1[CH:8]=[C:7]([S:9]C#N)[CH:6]=[CH:5][C:3]=1[NH2:4].O.O.O.O.O.O.O.O.O.[S-2].[Na+].[Na+].Cl>C(O)C.O>[Cl:1][C:2]1[CH:8]=[C:7]([SH:9])[CH:6]=[CH:5][C:3]=1[NH2:4]

Komponenten

6

Edukt 3

HCID 313Hydrochloric AcidHCID 73972Sodium sulfide nonahydrateHCID 5911252-CHLORO-4-THIOCYANATOANILINE

Produkt 1

HCID 198585664-Amino-3-chlorobenzenethiol

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 962WaterLösungsmittel2×

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

A solution of 2-chloro-4-thiocyanoaniline (36.9 g., 0.20 mole) in ethanol (100-200 ml.) is added to a stirred solution of sodium sulfide nonahydrate (48.04 g., 0.20 mole) in water (100 ml.) and the mixture warmed (50° C.) for 90 minutes. The cool reaction mixture is poured into water (1 liter) and dilute hydrochloric acid added to bring the pH up to 6.0-6.5. The product is extracted with ether, the ether washed with water and then dried. Removal of the drying agent and ether leaves 2-chloro-4-mercaptoaniline as a yellow oil.

Aufarbeitung

  1. customThe cool reaction mixture
  2. additionadded
  3. extractionThe product is extracted with ether
  4. washthe ether washed with water
  5. customdried
  6. customRemoval of the drying agent and ether

Quellen und Nachweise

ORD-Eintrag
ord-8b2d0530f3464ae095be8cceb561d521
Quelldatensatz
uspto-grants-1990_04
Patentnummer
US04913728

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