Ethanol → HCID 3735222, compound

HRID 2072655Notes

Reaction equation

HRID 2072655 reaction equation
C([O:3][C:4]([C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][O:29]C(=O)C)=[CH:14][CH:13]=2)=[CH:8][CH:7]=1)=[O:5])C.[OH-].[Na+].C(O)C>O>[OH:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][O:18][C:15]1[CH:16]=[CH:17][C:12]([C:9]2[CH:10]=[CH:11][C:6]([C:4]([OH:5])=[O:3])=[CH:7][CH:8]=2)=[CH:13][CH:14]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 538202524'-(10-Acetyloxydecyloxy)biphenyl-4-carboxylic acid ethyl ester

Product 1

HCID 3735222HCID 3735222, compoundYield 97.3%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

30 m moles (13.2 g) of the above 4'-(10-acetyloxydecyloxy) biphenyl-4-carboxylic acid ethyl ester and 10 g of sodium hydroxide were stirred for 10 min. at 70° C. in a mixed solvent of 40 ml of ethanol and 80 ml of water. After the reaction, the reaction solution was concentrated to obtain 10.8 g of 4'-(10-hydroxydecyloxy)biphenyl-4-carboxylic acid. (yield: 97%)

Workup

  1. customAfter the reaction
  2. concentrationthe reaction solution was concentrated

Sources & evidence

ORD record
ord-1d61dd5f42d54ecf82da2f024943d1e6
Source dataset
uspto-grants-1990_04
Patent number
US04913839

Reaction notes

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