Sulfuric Acid → 3-Ethylbenzophenone

HRID 2072868Notes

Reaction equation

HRID 2072868 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]([CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:6]=[CH:7][CH:8]=1)[CH3:2].[Mn]([O-])(=O)(=O)=[O:17].[K+].S(=O)(=O)(O)O.S([O-])(O)=O.[Na+]>O>[CH2:1]([C:3]1[CH:4]=[C:5]([CH:6]=[CH:7][CH:8]=1)[C:9]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:17])[CH3:2]

Participants

6

Reactant 4

HCID 1118Sulfuric AcidHCID 392181-Benzyl-3-ethylbenzeneHCID 516875Potassium PermanganateHCID 23665763Sodium Bisulfite

Product 1

HCID 5837303-EthylbenzophenoneYield 97%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In 200 ml of water, 19.7 g of the fraction containing (3-ethylphenyl)phenylmethane obtained in the above alkylation was suspended. With stirring the suspension, 2 liter of an 1.6% aqueous solution of potassium permanganate was dropped. After the dropping, the stirring was continued for about 10 hours at room temperature. After this mixture was acidified with concentrated sulfuric acid, sodium hydrogensulfite powder was added until the reaction mixture became transparent from brown and it was extracted with benzene. After drying the benzene layer with anhydrous magnesium sulfate, 3-ethylbenzophenone was obtained in a yield of 97% by reduced pressure distillation.

Workup

  1. customobtained in the above alkylation
  2. additionwas dropped
  3. additionwas added until the reaction mixture
  4. extractionwas extracted with benzene
  5. dry with materialAfter drying the benzene layer with anhydrous magnesium sulfate

Sources & evidence

ORD record
ord-5b992be44d114cc4843a6c5ff8f1ad58
Source dataset
uspto-grants-1990_04
Patent number
US04914242

Reaction notes

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