Glutaric anhydride → HCID 19857816, compound

HRID 2073163Notes

Reaction equation

HRID 2073163 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[C:13]2=[N:14][C:15]3[C:20]([N:21]=[C:12]2[C:11]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]1=2)=[CH:19][CH:18]=[CH:17][CH:16]=3.[C:22]1(=O)[O:28][C:26](=[O:27])[CH2:25][CH2:24][CH2:23]1>>[C:22]1(=[O:28])[N:1]([CH2:2][CH2:3][CH2:4][N:5]2[C:13]3=[N:14][C:15]4[C:20]([N:21]=[C:12]3[C:11]3[CH:10]=[CH:9][CH:8]=[CH:7][C:6]2=3)=[CH:19][CH:18]=[CH:17][CH:16]=4)[C:26](=[O:27])[CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 7940Glutaric anhydrideHCID 4914434HCID 4914434, compound

Product 1

HCID 19857816HCID 19857816, compound

Procedure

6-(3-aminopropyl)-6H-indolo(2,3-b)quinoxaline (2.77 g, 0.01 mole) is heated (3 hours, 170° C.) with glutaric acid anhydride (1.14 g, 0.01 mole) and then the melt is allowed to cool and recrystallization from acetonitrile is carried out. Yield: 3,43, (92%) mp. 312°-314° C.

Workup

  1. temperatureto cool
  2. customrecrystallization from acetonitrile

Sources & evidence

ORD record
ord-d25591b8cb904726b88c7a8811cb1be4
Source dataset
uspto-grants-1990_04
Patent number
US04916124

Reaction notes

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