反应详情

A mixture of 4.0 g of 7-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile (prepared as described in Example 7 of U.S. Pat. No. 4,236,005) and 40 ml of concentrated sulfuric acid was stirred at room temperature for 16 hours. The solution was then carefully poured into ice with stirring and the mixture was carefully made just basic with concentrated ammonium hydroxide. The solid was collected by filtration and recrystallized from dichloromethane to give pale yellow needles m.p. 236°-238.5° C.

1. customprepared
2. additionThe solution was then carefully poured into ice
3. filtrationThe solid was collected by filtration
4. customrecrystallized from dichloromethane