Hydrochloric Acid → HCID 86743843, compound

HRID 2073230Notes

Reaction equation

HRID 2073230 reaction equation
C[O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([N:11]([C:13](=[O:25])[C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[C:16]([S:21](=[O:24])(=[O:23])[NH2:22])[CH:15]=2)[NH2:12])=[C:7]([N+:26]([O-:28])=[O:27])[CH:6]=1)=[O:4].Cl>[OH-].[Na+]>[C:3]([C:5]1[CH:10]=[CH:9][C:8]([N:11]([C:13](=[O:25])[C:14]2[CH:19]=[CH:18][C:17]([Cl:20])=[C:16]([S:21](=[O:24])(=[O:23])[NH2:22])[CH:15]=2)[NH2:12])=[C:7]([N+:26]([O-:28])=[O:27])[CH:6]=1)([OH:4])=[O:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86743844HCID 86743844, compound

Product 1

HCID 86743843HCID 86743843, compoundYield 92.5%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

25.7 g of 4-methoxycarbonyl-2-nitro-N-(4'-chloro-3'-sulfamoylbenzoyl)phenylhydrazine were stirred with 120 ml of 2N sodium hydroxide solution at 50° C. for 4 hours. After cooling down, the pH value of the dark violet solution was adjusted to 5 by adding 2N hydrochloric acid. The yellow precipitate was filtered by suction, washed with water and dried at 80° C. to give 23 g (92.5%) of 4-carboxy-2-nitro-N-(4'-chloro-3'-sulfamoyl-benzoyl)phenylhydrazine as a yellow powder, m.p.: 273°-275° C. (with decomposition).

Workup

  1. temperatureAfter cooling down
  2. filtrationThe yellow precipitate was filtered by suction
  3. washwashed with water
  4. customdried at 80° C.

Sources & evidence

ORD record
ord-7db515bc8d894b348ba56031b8ed1237
Source dataset
uspto-grants-1990_04
Patent number
US04916149

Reaction notes

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