反应详情

20 ml of hydrazine hydrate were added to the suspension of 52.33 g of 4-chloro-3-nitrobenzophenone in 200 ml of abs. ethanol under stirring. The reaction mixture was stirred at room temperature for 75 minutes, then slowly heated to the boiling point. After completion of the violent reaction, the mixture was refluxed for an additional 1 hour. After cooling down, the crystals were filtered by suction, thoroughly washed with water and dried at 80° C. Thus, 38.62 g (75%) of 4-benzoyl-2-nitrophenylhydrazine were obtained as orange-red crystals, m.p.: 163°-164° C.

1. temperatureslowly heated to the boiling point
2. customAfter completion of the violent reaction
3. temperaturethe mixture was refluxed for an additional 1 hour
4. temperatureAfter cooling down
5. filtrationthe crystals were filtered by suction
6. washthoroughly washed with water
7. customdried at 80° C