HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 4-(4-Chlorophenylsulfonylamino)pyrrolidine trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-(4-Chlorophenylsulfonylamino)pyrrolidine | HCID 17914505 | — |
| Product | 4-(4-Chlorophenylsulfonylamino)pyrrolidine trifluoroacetate | HCID 86743849 | — |
Reaction Steps
(2S,4R)-1-t-Butoxycarbonyl-2-[(E and Z)-5-carboxy-5-methyl-1-hexenyl]-4-(4-chlorophenylsulfonylamino)pyrrolidine obtained in Example 20(1) was dissolved in 75% aqueous trifluoroacetic acid (8 ml) and the solution was stirred at room temperature for 1 hour. The solvent was evaporated in vacuo to give (2S,4R)-2-[(E and Z)-5-carboxy-5-methyl-1-hexenyl]-4-(4-chlorophenylsulfonylamino)pyrrolidine trifluoroacetate as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04916152 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-3b08eeb31e774b7ab47470e803e6d7ed |
| Source note | uspto-grants-1990_04 |