HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 19857170, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Piperidineethanol | HCID 73953 | — |
| Reactant | 1,1'-(4-Bromobutylidene)bis[4-fluorobenzene] | HCID 93763 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19857170 | HCID 19857170 | — |
Reaction Steps
20 g (62 mmol) of 4,4-bis(4-fluorophenyl)butyl bromide, 8.8 g (68 mmol) of 4-hydroxyethylpiperidine, 12.5 g (124 mmol) of triethylamine and 0.1 g of potassium iodide were stirred in 200 ml of absolute dimethylformamide at 80° C. for 4.5 hours. The solvent was stripped off in vacuo, the residue was taken up in methylene chloride, the mixture was extracted by shaking with 2N HCl, water and NaCl solution and the extract was dried and concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04918073 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-93b725a4099c46ceafa5c98225c72c9f |
| Source note | uspto-grants-1990_04 |