Sodium Carbonate → HCID 240976, compound

HRID 2073530Notes

Reaction equation

HRID 2073530 reaction equation
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]=[CH:12][C:13]2[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[N:14]=2)=[CH:7][CH:6]=1)(=O)C.C([O-])([O-])=O.[Na+].[Na+].[NH4+].[OH-]>CO>[N:14]1[C:15]2[C:20](=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:21]=[CH:22][C:13]=1[CH:12]=[CH:11][C:8]1[CH:7]=[CH:6][C:5]([OH:4])=[CH:10][CH:9]=1

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 14923Ammonium HydroxideHCID 54521202HCID 54521202, compound

Product 1

HCID 240976HCID 240976, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a suspension of 28.2 g of 2-(2-(4-acetoxyphenyl)ethenyl)quinoline in 500 ml of methanol is added 2.58 g (0.25 equiv.) of Na2CO3. This is stirred for 24 hours at room temperature. To this reaction mixture is then added 200 ml of pH7 buffer (25% NH4OH) and the precipitate that forms is filtered off, washed with methanol and dried to give 4-[2-(quinolin-2-yl)ethenyl]phenol (M.P. 268°-270° C.).

Workup

  1. filtrationthe precipitate that forms is filtered off
  2. washwashed with methanol
  3. customdried

Sources & evidence

ORD record
ord-e50f2b3c76284d3c8ff12fae19f8c09d
Source dataset
uspto-grants-1990_04
Patent number
US04918081

Reaction notes

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