HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 53970677, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 70362505 | HCID 70362505 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 53970677 | HCID 53970677 | — |
Reaction Steps
The crude product is purified by column chromatography to give ethyl 4-(2-(4-(2-(7-chloroquinolin-2-yl)ethenyl)phenoxymethyl)phenoxy)-4-carbethoxybutyrate. The ester is treated with 1N NaOH solution (30 mL) in dioxane overnight. The reaction mixture is then acidified, and purified by flash chromatography which gives 4-(2-(4-(2-(7-chloroquinolin-2-yl)ethenyl)phenoxymethyl)phenoxy)-4-carboxybutyric acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04918081 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-bd93f2f0a036448aa4c89aa675cfe30c |
| Source note | uspto-grants-1990_04 |