Water → HCID 19890426, compound

Participants

Reaction Steps

In a round-bottomed flask, 0.27 g of sodium hydroxide and 1 ml of water were placed, 3 ml of methanol was added and then 0.7 g of ethyl p-(3-trifluoromethylheptyloxy)benzoate was added thereto, followed by 4 hours of reaction at 50° C. Then, water was added to the system, and methanol was distilled off, followed by addition of 6N-hydrochloric acid to recover a precipitated crystal. The crystal was dried in a desiccator to obtain 0.55 g of p-(3-trifluoromethylheptyloxy)benzoic acid ◯4 . (Yield: 90%).

Provenance & Evidence