HuagongsheHuagongshe Chemistry Print Report · For research reference only
2',4'-Dichloroacetophenone → 2-Bromo-1-(2,4-dichlorophenyl)ethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2',4'-Dichloroacetophenone | HCID 16693 | — |
| Reactant | Bromine | HCID 24408 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Bromo-1-(2,4-dichlorophenyl)ethan-1-one | HCID 75828 | — |
Reaction Steps
To 100 mL of ethyl ether is added 1-(2,4-dichlorophenyl)ethanone (18.9 g, 0.1 mol) and bromine (16 g, 0.1 mmol). Monitor the reaction by thin-layer chromatography. Upon completion wash the organic phase with 100 mL H2O and 50 mL brine. Dry the organic phase over Na2SO4. Filter the drying agent and evaporate the solvent in vacuo to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04920116 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-702fed60d9b9440c8f94e1ebe74d7a9f |
| Source note | uspto-grants-1990_04 |