Cyclohexylamine → HCID 19855953, compound

HRID 2073743Notes

Reaction equation

HRID 2073743 reaction equation
[N:1]([CH2:4][C:5]([C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[C:9]([O:17][CH3:18])[CH:8]=1)=O)=[N+:2]=[N-:3].[CH:19]1([NH2:25])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1.[BH3-]C#N.[Na+]>>[N:1]([CH2:4][CH:5]([C:7]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([O:15][CH3:16])=[C:9]([O:17][CH3:18])[CH:8]=1)[NH:25][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1)=[N+:2]=[N-:3]

Participants

4

Reactant 3

HCID 7965CyclohexylamineHCID 5003444Sodium cyanoborohydrideHCID 19855932HCID 19855932, compound

Product 1

HCID 19855953HCID 19855953, compound

Procedure

In a manner similar to Preparation 21 react 2-azido-1-(3,4,5-trimethoxyphenyl)ethanone with cyclohexanamine and NaCNBH3 to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 21

Sources & evidence

ORD record
ord-c5a3a4265219489398074354b564f133
Source dataset
uspto-grants-1990_04
Patent number
US04920116

Reaction notes

Loading…