Sodium cyanoborohydride → HCID 16643585, compound

HRID 2073749Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9](=O)[CH2:10][N:11]([CH3:13])[CH3:12].[BH3-]C#[N:17].[Na+]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([NH2:17])[CH2:10][N:11]([CH3:13])[CH3:12]

Participants

Reactant 2

HCID 5003444Sodium cyanoborohydride

HCID 19855916HCID 19855916, compound

Product 1

HCID 16643585HCID 16643585, compound

Procedure

In a manner similar to Preparation 21 react 1-(2,4-dichlorophenyl)-2-(dimethylamino)ethanone with NH4OAc and NaCNBH3 to obtain the title compound.

Workup

customIn a manner similar to Preparation 21

Sources & evidence

ORD record: ord-8ca91405926a46eaa6f417e05cc6061e
Source dataset: uspto-grants-1990_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04920116

Reaction notes

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