反应详情

To a suspension of 2-methyl-6-methoxycarbonylaminobenzyl alcohol (29.19 g) in methylene chloride (290 ml) was added dropwise thionyl chloride (11.46 ml) at room temperature and the resultant mixture was stirred for 2 hours. After the solvent was evaporated in vacuo, n-hexane was added to the residue to give precipitates. The precipitates were collected by filtration and dried to give 2-methyl-6-methoxycarbonylaminobenzyl chloride (28.26 g).

1. customAfter the solvent was evaporated in vacuo, n-hexane
2. additionwas added to the residue
3. customto give
4. customprecipitates
5. filtrationThe precipitates were collected by filtration
6. customdried