Thionyl Chloride → HCID 14368348, compound

HRID 2073799Notes

Reaction equation

HRID 2073799 reaction equation
[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([NH:10][C:11]([NH2:13])=[O:12])[C:3]=1[CH2:4]O.S(Cl)([Cl:16])=O>C(Cl)Cl>[CH3:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([NH:10][C:11]([NH2:13])=[O:12])[C:3]=1[CH2:4][Cl:16]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 143684562-Methyl-6-ureidobenzyl alcohol

Product 1

HCID 14368348HCID 14368348, compoundYield 59.9%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of 2-methyl-6-ureidobenzyl alcohol (1 g) and thionyl chloride (0.66 g) in methylene chloride (20 ml) was stirred for 2 hours at room temperature and evaporated in vacuo. The residue was washed with water and dried in a desiccator to give 2-methyl-6-ureidobenzyl chloride (0.66 g).

Workup

  1. customevaporated in vacuo
  2. washThe residue was washed with water
  3. customdried in a desiccator

Sources & evidence

ORD record
ord-48fe8fb720834df79d6fe6d6721b51c3
Source dataset
uspto-grants-1990_04
Patent number
US04920129

Reaction notes

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